8.08154

Thionyl chloride

for synthesis

• Synonyme(s) : Thionyl chloride, Sulfurous acid dichloride, Sulfurous oxychloride
• Formule empirique (notation de Hill): Cl₂OS
• Numéro CAS: 7719-09-7
• Poids moléculaire : 118.97
• Numéro MDL: MFCD00011449
• Code UNSPSC : 12352307
• Numéro de classement CE : 231-748-8
• Nomenclature NACRES : NA.22

Propriétés

• Pression de vapeur: 121 hPa ( 20 °C)
• Niveau de qualité: 200
• Forme: liquid
• Puissance: 324 mg/kg LD₅₀, oral (Rat)
• Point d'ébullition: 76 °C/1013 hPa
• Pf: -104.5 °C
• Densité: 1.64 g/cm³ at 20 °C
• Température de stockage: 2-30°C
• InChI: 1S/Cl2OS/c1-4(2)3
• Clé InChI: FYSNRJHAOHDILO-UHFFFAOYSA-N

Description

Description générale

Thionyl chloride is an inorganic acid chloride. It is mainly used as a chlorinating agent in organic synthesis for the production of organochlorine compounds.

Application

Thionyl chloride can be used as a catalyst to synthesize:

• 4-(sulfinylamino)-1,2,4-triazole by reacting with 4-amino-1,2,4-triazole.
• Isothiazolopyrimidines from aminouracils via cyclization reaction.
• 1,2,6-triazine S-oxides by reacting with diimines via condensation reactions in the presence of pyridine.
• 2-oxo-1,3,2-dioxathianes by condensation reaction with alkane-1,3-diols.
• Cyclic sulfites by reacting with nitroglycols.
• Microporous organic polymers by aldol self-condensation reaction of di and multiacetyl building blocks.

Remarque sur l'analyse

Assay (argentometric): ≥ 99.0 %
Identity (IR): passes test

Informations sur la sécurité

• Pictogrammes: GHS05,GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H302 - H314 - H331 - H335
• Conseils de prudence: P261 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
• Organes cibles: Respiratory system
• Risques supp: EUH014 - EUH029
• Code de la classe de stockage: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable