609312

Thyroglobulin, Human Thyroid

• Synonyme(s) : Thyroglobulin, Human Thyroid
• Numéro CAS: 9010-34-8
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: human thyroid
• Niveau de qualité: 100
• Pureté: ≥95% (PAGE)
• Forme: lyophilized
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C

Description

Description générale

Native thyroglobulin, consisting of two polypeptide monomers of 33 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins.

Native thyroglobulin, consisting of two polypeptide monomers of 330 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins. When subjected to native PAGE this protein shows a band at

~660 kDa, representing the dimeric form, and another band at ~330 kDa, representing the monomeric form.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

Lyophilized from 20 mM NH₄HCO₃.

Notes préparatoires

Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Reconstitute in phosphate buffer, containing 150 mM NaCl, pH >7.0.

Autres remarques

Rawitch, A.B., et al. 1993. Arch. Biochem. Biophys. 300, 271.
Black, E.G., and Sheppard, M.C. 1991. Clin. Endocrinol. 35, 519.
Spiro, R.G., and Bhoyroo, V.D. 1988. J. Biol. Chem. 263, 14351.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3