178456

Apolipoprotein B, Human Plasma, Low-Density Lipoprotein

Native apolipoprotein B from human plasma. It is a dominant protein constituent of LDL and VLDL. Acts as a ligand for LDL receptor, directing clearance of LDL from plasma to the liver.

• Synonyme(s) : Apo B, Apo B-100
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (SDS-PAGE)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Native apolipoprotein B from human plasma. Native apoplipoprotein B from human plasma. Dominant protein constituent of LDL and also present in VLDL. Ligand for the LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Produced by the liver. Mean serum concentration: 950 µg/ml.

Native apolipoprotein B from human plasma. Produced by the liver, and is a dominant protein constituent of LDL that is also present in VLDL. Ligand for LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Mean serum concentration: 950 µg/ml. Higher levels are reported in familial hyperlipidemia, obesity, and diabetes.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

Lyophilized from 50 mM Na₂CO₃, 50 mM NaCl, 10 mM sodium deoxycholate, pH 10.0.

Notes préparatoires

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Please refer to the label for lot-specific reconstitution volume.

Autres remarques

Jiang, X.C., et al. 2001. Nat. Med.1, 847.
Zhou, M., et al. 1995. J. Biol. Chem.270, 25220.
Sivaram, P., et al. 1993. J. Biol. Chem.269, 9409.
Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d′importation et d′exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L′acheteur (c′est-à-dire l′utilisateur FINAL) est tenu d′obtenir une autorisation d′importation auprès du ministère français de la recherche, mentionné à l′article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l′autorisation d′importation requise.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable