126654
Albumin, Human Serum, Non-denatured
Synonyme(s) :
Albumin, Human Serum, Non-denatured
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About This Item
Produits recommandés
Pureté
≥95% (SDS-PAGE)
Forme
lyophilized solid (Salt-free)
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
pl
4.7
Solubilité
water: 20 mg/mL
Conditions d'expédition
ambient
Température de stockage
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
Clé InChI
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Description générale
High purity plasma protein prepared under non-denaturing conditions.
Human serum albumin (HSA) is the most abundant protein present in the plasma. It is a monomeric multi-domain macromolecule comprising three homologous domains, numbered I, II, and III. Each domain consists of subdomains A and B with common structural motifs. The HSA gene is mapped to the human chromosome 4q13.3.
Application
Albumin, human serum, non-denatured has been used:
- to determine the contribution of albumin protein complexes to esterase activity in saliva,
- in tris buffer for monomer degradation studies and in protein adhesion assay
- to study the effect of Cu2+ and Zn2+ ions on human serum albumin interaction with plasma unsaturated fatty acids
Actions biochimiques/physiologiques
Human serum albumin (HSA) functions as a carrier for fatty acids, steroids, and thyroid hormones. It is used as a supplement in cell culture medium to produce vaccines and pharmaceuticals. HSA is a potential biomarker for various diseases, like cancer, rheumatoid arthritis, ischemia, and post-menopausal obesity. It is also used to treat surgical blood loss, trauma, hemorrhage, and cardiopulmonary bypass. HSA is implicated in biological applications such as implantable biomaterials, surgical adhesives and sealants, and bio chromatography.
Avertissement
Toxicity: Standard Handling (A)
Notes préparatoires
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Autres remarques
Travis, J., and Pannell, R. 1973. Clin. Chem. Acta49, 49.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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