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Merck
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Key Documents

12-151

Sigma-Aldrich

PKA Inhibitor Peptide

lyophilized powder, for Neuroscience applications

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About This Item

Code UNSPSC :
12352202
eCl@ss :
32160405
Nomenclature NACRES :
NA.41

product name

PKA Inhibitor peptide, The PKA Inhibitor peptide controls the biological activity of PKA. This small molecule/inhibitor is primarily used for Neuroscience applications.

Niveau de qualité

100

Forme

lyophilized powder

Fabricant/nom de marque

Upstate®

Technique(s)

activity assay: suitable (kinase)

Numéro d'accès NCBI

NM_002730.3
NM_207518.1

Numéro d'accès UniProt

P17612

Conditions d'expédition

wet ice

Actions biochimiques/physiologiques

Protein Target: PKA
Target Sub-Family: AGC

Qualité

Routinely evaluated by inhibition of PKA catalytic subunit (14-114).

Forme physique

Lyophilized powder (from H2O)

Stockage et stabilité

Lyophilized: Stable for 2 years at -20°C . Rehydrated: Stable for 1 year at -20°C.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Y I Lee et al.
The Journal of biological chemistry, 276(20), 16969-16977 (2001-03-30)
The hepatitis B virus-X (HBx) protein is known as a multifunctional protein that not only coactivates transcription of viral and cellular genes but coordinates the balance between proliferation and programmed cell death, by inducing or blocking apoptosis. In this study
Heterogeneity in beta-adrenergic receptor kinase expression in the lung accounts for cell-specific desensitization of the beta2-adrenergic receptor
McGraw, D. W. and Liggett, S. B.
The Journal of Biological Chemistry, 272, 7338-7344 (1997)
H L Lai et al.
The Journal of biological chemistry, 272(8), 4970-4977 (1997-02-21)
We have previously reported that phosphorylation of adenylyl cyclase type VI (AC6) may result in the suppression of adenylyl cyclase activity during desensitization of the A2a-adenosine receptor-mediated cAMP response (A2a desensitization) in rat pheochromocytoma PC12 cells. In the present study
Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein.
Glass, D B, et al.
The Journal of Biological Chemistry, 264, 8802-8810 (1989)
Christian M Smolko et al.
Scientific reports, 9(1), 19409-19409 (2019-12-21)
Protein kinases are enzymes whose abundance, protein-protein interactions, and posttranslational modifications together determine net signaling activity in cells. Large-scale data on cellular kinase activity are limited, because existing assays are cumbersome, poorly sensitive, low throughput, and restricted to measuring one

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