09-796

Anti-PADI4 Antibody, CT

from rabbit

• Synonyme(s) : HL-60 PAD, PADI-H protein, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase, Protein-arginine deiminase type-4
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: saturated ammonium sulfate (SAS) precipitated
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: human
• Technique(s): ELISA: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_036519
• Numéro d'accès UniProt: Q9UM07
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PADI4(23569)

Description

Description générale

PADI4 (Protein-arginine deiminase type-4) is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalysis of the deimination of the arginine residues. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Spécificité

The antibody recognizes PADI4 at and around the C-terminus.

Immunogène

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of PADI4.

Application

Anti-PADI4 Antibody, C-terminus is an antibody against PADI4 for use in WB, ELISA.

ELISA: A 1:1000 dilution of a previous lot was used on ELISA.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Qualité

Evaluated by western blot on HEK293 cell lysate.

Western Blotting Analysis: 1:25-1:500 dilution of this antibody detected PADI4 in HEK293 cell lysate.

Description de la cible

~74 kDa

Forme physique

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Stockage et stabilité

Stable for 6 months at 2-8ºC from date of receipt. For long term storage, store at -20ºC

Remarque sur l'analyse

Control
HEK293 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable