06-937
Anti-phospho-STAT6 (Tyr641) Antibody
Upstate®, from rabbit
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Espèces réactives
human, mouse
Fabricant/nom de marque
Upstate®
Technique(s)
western blot: suitable
Isotype
IgG
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
phosphorylation (pTyr641)
Informations sur le gène
human ... STAT6(6778)
Spécificité
phospho-STAT6
Immunogène
peptide corresponding to amino acids 631-645 of human STAT6 (C-PEQMGKDGRGpYVPAT)
Application
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
This Anti-phospho-STAT6 (Tyr641) Antibody is validated for use in WB for the detection of phospho-STAT6 (Tyr641).
Qualité
routinely evaluated by immunoblot on lysates of HepG2 cells, serum starved, then stimulated with IL-4
Description de la cible
100kDa
Forme physique
0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
Format: Purified
Protein A purified
Stockage et stabilité
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Defective GATA-3 expression in Th2 LCR-deficient mice.
Soo Seok Hwang,Kiwan Kim,Gap Ryol Lee
Biochemical and biophysical research communications null
F W Quelle et al.
Molecular and cellular biology, 15(6), 3336-3343 (1995-06-01)
By searching a database of expressed sequences, we identified a member of the signal transducers and activators of transcription (Stat) family of proteins. Human and murine full-length cDNA clones were obtained and sequenced. The sequence of the human cDNA was
Giulia Veltri et al.
Cancers, 13(15) (2021-08-08)
Lymphoblastic lymphoma (LBL) is the second most common type of non-Hodgkin lymphoma in childhood, mainly of T cell origin (T-LBL). Although current treatment protocols allow a complete remission in 85% of cases, the second-line treatment overall survival for patients with
Tetsuya Kubota et al.
Nature communications, 9(1), 4863-4863 (2018-11-20)
M2a-subtype macrophage activation is known to be impaired in obesity, although the underlying mechanisms remain poorly understood. Herein, we demonstrate that, the IL-4/Irs2/Akt pathway is selectively impaired, along with decreased macrophage Irs2 expression, although IL-4/STAT6 pathway is maintained. Indeed, myeloid
Jason C O'Connor et al.
Journal of immunology (Baltimore, Md. : 1950), 178(11), 6886-6893 (2007-05-22)
Chronic elevation of proinflammatory markers in type 2 diabetes (T2D) is well defined, but the role of anti-inflammatory cytokines in T2D is less clear. In this study, we report that normal IL-4-dependent elaboration of IL-1 receptor antagonist (IL-1RA) requires IRS-2-mediated
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