N-046
(+)-Norpseudoephedrine hydrochloride solution
100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Synonyme(s) :
Cathine hydrochloride
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About This Item
Formule empirique (notation de Hill):
C9H14ClNO
Numéro CAS:
Poids moléculaire :
187.67
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
certified reference material
Niveau de qualité
Forme
liquid
Caractéristiques
Snap-N-Spike®/Snap-N-Shoot®
Conditionnement
ampule of 1 mL
Fabricant/nom de marque
Cerilliant®
drug control
Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
Concentration
100 μg/mL in methanol (as free base)
Technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
Application(s)
forensics and toxicology
Format
single component solution
Température de stockage
−20°C
Chaîne SMILES
Cl.C[C@H](N)[C@@H](O)c1ccccc1
InChI
1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9+;/m0./s1
Clé InChI
DYWNLSQWJMTVGJ-DKXTVVGFSA-N
Description générale
A certified reference solution suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications, from clinical toxicology and forensic analysis to urine drug testing and sports testing. (+)-Norpseudoephedrine, also known as cathine, is a psychoactive stimulant of the phenethylamine and amphetamine classes.
Application
- Phytochemical Profiling and Therapeutic Activities: (+)-Norpseudoephedrine hydrochloride solution is utilized in phytochemical profiling studies, specifically analyzing the toxicity, wound healing, analgesic, and anti-inflammatory properties of Musa paradisiaca L. stem extracts. This research enhances the understanding of natural products in pharmaceutical applications, particularly for their therapeutic potential (Ekweogu et al., 2024).
- Chiral Analysis of Stimulant Drugs: The solution is critical in the development and application of a chiral high-performance liquid chromatography-tandem mass spectrometry method for forensic analysis. This method is used to determine the presence of related amphetamine-type stimulants, providing essential data for law enforcement and drug regulation agencies (Schwelm et al., 2020).
- Microbial Production of Phenylalkylamines: (+)-Norpseudoephedrine hydrochloride serves as a biochemical tool in studies focused on the microbial production of ephedrine and pseudoephedrine, revealing significant implications for the manufacturing of pharmaceuticals and enhancing our understanding of metabolic pathways (Morris et al., 2018).
- Improved Detection Methods for Cathinones: This compound is integral to the improved gas chromatography method for detecting active principles in Catha edulis, demonstrating its utility in identifying and quantifying natural sources of cathinones, which are important for both medical research and drug enforcement (Dell′acqua et al., 2013).
- Chiral Capillary Electrophoresis: Used in chiral capillary electrophoresis for methamphetamine profiling, (+)-Norpseudoephedrine hydrochloride solution assists in distinguishing isomers in forensic samples, which is critical for the precise identification of controlled substances in forensic settings (Iwata et al., 2013).
Informations légales
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Mention d'avertissement
Danger
Mentions de danger
Classification des risques
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Code de la classe de stockage
3 - Flammable liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
49.5 °F - closed cup
Point d'éclair (°C)
9.7 °C - closed cup
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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John S Chappell et al.
Forensic science international, 195(1-3), 108-120 (2009-12-29)
A primary concern with the forensic analysis of the khat plant (Catha edulis) has been the need to preserve the principle psychoactive component, cathinone, which converts to the less-active substance, cathine, after harvesting. The loss of cathinone has serious legal
Hyeon-Kyu Lee et al.
The Journal of organic chemistry, 77(12), 5454-5460 (2012-05-25)
Each of the enantiomers of both norephedrine and norpseudoephedrine were stereoselectively prepared from the common, prochiral cyclic sulfamidate imine of racemic 1-hydroxy-1-phenyl-propan-2-one by employing asymmetric transfer hydrogenation (ATH) catalyzed by the well-defined chiral Rh-complexes, (S,S)- or (R,R)-Cp*RhCl(TsDPEN), and HCO(2)H/Et(3)N as
Carlos Castillo-Henkel et al.
Proceedings of the Western Pharmacology Society, 53, 33-36 (2010-01-01)
Here we contrast the vascular smooth muscle contractility produced by D-nor-pseudoephedrine, alone or combined with triiodothyronine, on the aorta and coronary vasculature of the rat. At high concentrations (greater than those found in normal therapeutic dosing) D-nor-pseudoephedrine contracted the aorta.
Saba Kassim et al.
Journal of ethnopharmacology, 140(1), 193-196 (2012-01-17)
Khat chewing amongst the UK communities originating from Yemen and the East African coast is suggested to create dependency through its main stimulant components (cathinone, norephedrine and norpseudoephedrine) on the central nervous system. To validate self-reported khat chewing behaviours by
Richard Hoffman et al.
Journal of ethnopharmacology, 132(3), 554-563 (2010-06-18)
Although there is a rich body of research available regarding the effect of acute and chronic khat dosing in animal models, research on the behavioral and cognitive effects of khat in human subjects is not extensive and several of the
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