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Key Documents

LM1601

Avanti

17:1 Lyso PC

Avanti Research - A Croda Brand LM1601, methanol solution

Synonyme(s) :

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphocholine

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About This Item

Formule empirique (notation de Hill):
C25H50NO7P
Numéro CAS:
Poids moléculaire :
507.64
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Forme

methanol solution

Conditionnement

pkg of 1 × 1 mL (LM1601-1EA)

Fabricant/nom de marque

Avanti Research - A Croda Brand LM1601

Concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O

Description générale

Lysophosphatidylcholine (LPC) is a polar lipid, localized to the cell membranes of oxidized lipoproteins.

Application

17:1 Lyso PC has been used as an LIPID MAPS internal standard for lipid extraction from serum and quantification in liquid chromatography mass-spectrometry (LC-MS) analysis.

Actions biochimiques/physiologiques

Lysophosphatidylcholine (LPC) is a bioactive molecule involved in various biological processes such as vascular reproduction, development and myelination. It is associated to the progression of atherosclerosis, with findings of high concentration of LPC in the lesions/plaques. Higher levels of LPC are also found in oxidatively damaged low-density lipoprotein (oxLDL) indicating cardiovascular disease. LPC is known to be implicated in neuronal diseases and cancer.

Conditionnement

2 mL Amber Glass Sealed Ampule (LM1601-1EA)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup


Certificats d'analyse (COA)

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Victoria Meslier et al.
Gut (2020-02-23)
This study aimed to explore the effects of an isocaloric Mediterranean diet (MD) intervention on metabolic health, gut microbiome and systemic metabolome in subjects with lifestyle risk factors for metabolic disease. Eighty-two healthy overweight and obese subjects with a habitually
Judith Simcox et al.
Cell metabolism, 26(3), 509-522 (2017-09-07)
Cold-induced thermogenesis is an energy-demanding process that protects endotherms against a reduction in ambient temperature. Using non-targeted liquid chromatography-mass spectrometry-based lipidomics, we identified elevated levels of plasma acylcarnitines in response to the cold. We found that the liver undergoes a
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to

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