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Key Documents

890717O

Avanti

14:1 EPC (Tf Salt)

Avanti Research™ - A Croda Brand 890717O

Synonyme(s) :

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)

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About This Item

Formule empirique (notation de Hill):
C39H73F3NO11PS
Numéro CAS:
1246304-44-8
Poids moléculaire :
852.03
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Forme

liquid

Conditionnement

pkg of 1 × 10 mg (890717O-10mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 890717O

Type de lipide

transfection
cationic lipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Ethylphosphocholine (EPC) are amphiphilic cationic lipids containing hydrophilic headgroup and lipophilic tail.

Actions biochimiques/physiologiques

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (14:1 EPC) is less toxic and is biodegradable. It is known to possess efficient DNA transfection activity. 14:1 EPC is very closely identical to the natural triacylglyceride lipids.

Conditionnement

5 mL Clear Glass Sealed Ampule (890717O-10mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

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Mikhail A Galkin et al.
Journal of visualized experiments : JoVE, (134) (2018-04-24)
Detergents are indispensable for delivery of membrane proteins into 30-100 nm small unilamellar vesicles, while more complex, larger model lipid bilayers are less compatible with detergents. Here we describe a strategy for bypassing this fundamental limitation using fusogenic oppositely charged
Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.
Jinjun Shi et al.
Angewandte Chemie (International ed. in English), 50(31), 7027-7031 (2011-06-24)
Rumiana Koynova et al.
The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
Rumiana Koynova et al.
Molecular pharmaceutics, 6(3), 951-958 (2009-04-04)
Synthetic cationic lipids are widely used components of nonviral gene carriers, and the factors regulating their transfection efficiency are the subject of considerable interest. In view of the important role that electrostatic interactions with the polyanionic nucleic acids play in
Rumiana Koynova et al.
Biochimica et biophysica acta, 1768(2), 375-386 (2006-12-13)
Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The large magnitude of the synergy
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