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Key Documents

888787D

Avanti

PAMPA Lipid Blend I

Avanti Research™ - A Croda Brand

Synonyme(s) :

PAMPA Lipid Blend I, DOPC:Stearic Acid (80:20, w/w) in Dodecane with 1% Ethanol for use in PAMPA assay, dodecane

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About This Item

Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Forme

liquid

Conditionnement

pkg of 1 × 3 mL (888787D-150mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Concentration

50 mg/mL (888787D-150mg)

Application(s)

microbiology

Type de lipide

phospholipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

PAMPA Lipid Blend I is a lipid solution in dodecane/ethanol. Once opened, the contents of the glass ampoule should be transferred to a glass container with PTFE-lined screw cap closure for storage at -20°C. The transfer should be performed with a glass syringe or pipette. The solution should not contact plastic, i.e., do not transfer with plastic pipette tip or store in plastic vials.

Application

The PAMPA Lipid Blend I has been used in the parallel artificial membrane permeability assay (PAMPA) for the formation of artificial membrane.

Actions biochimiques/physiologiques

The parallel artificial membrane permeability assay (PAMPA) is useful to study the oral absorption of drugs. It helps in specifying passive transcellular diffusion.

Conditionnement

5 mL Clear Glass Sealed Ampule (888787D-150mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H304

Classification des risques

Asp. Tox. 1

Risques supp

EUH066

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Li Di et al.
European journal of medicinal chemistry, 38(3), 223-232 (2003-04-02)
The recent advances in high throughput screening for biological activities and combinatorial chemistry have greatly expanded the number of drug candidates. Rapid screening for BBB penetration potential early in drug discovery programs provides important information for compound selection and guidance
Fangzhou Xie et al.
Bioorganic chemistry, 92, 103273-103273 (2019-09-21)
Protein tyrosine phosphatase 1B (PTP1B), a key negative regulator of insulin signaling, is considered as a promising and validated therapeutic target for type 2 diabetes mellitus (T2DM) and obesity. Upon careful study, a series of 2-ethoxy-4-(methoxymethyl)benzamide and 2-ethoxy-5-(methoxymethyl)benzamide analogs designed
High-throughput artificial membrane permeability studies in early lead discovery and development
Pharmacokinetic optimization in drug research (2001)
Fangzhou Xie et al.
European journal of medicinal chemistry, 164, 408-422 (2019-01-07)
Protein tyrosine phosphatase 1B (PTP1B) has been considered as a promising therapeutic target for type 2 diabetes mellitus (T2DM) and obesity due to its key regulating effects in insulin signaling and leptin receptor pathways. In this work, a series of

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