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Key Documents

141101C

Avanti

Brain Extract Polar

Avanti Research™ - A Croda Brand

Synonyme(s) :

Brain Polar Lipid Extract (Porcine)

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About This Item

Numéro CAS:
86088-88-2
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Forme

chloroform solution

Conditionnement

pkg of 1 × 4 mL (141101C-100mg)
pkg of 5 × 4 mL (141101C-500mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Concentration

25 mg/mL (141101C-100mg)
25 mg/mL (141101C-500mg)

Type de lipide

lipid extracts

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Brain Extract Polar comprises phosphatidylethanolamine as major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol.
Brain Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.

Application

Brain Extract Polar has been used as an artificial membrane solution component for permeability studies. It may be used for coating donor plate during parallel artificial membrane permeability assay (PAMPA) to study blood-brain barrier penetration. It may be used in liposome preparation for dynamin self-assembly assay.

Actions biochimiques/physiologiques

Brain lipid, especially the polar fraction plays a key role in the inhibition of prion seeded amyloid formation. Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes.

Conditionnement

5 mL Clear Glass Sealed Ampule (141101C-100mg)
5 mL Clear Glass Sealed Ampule (141101C-500mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Prediction of blood-brain barrier permeation of alpha-adrenergic and imidazoline receptor ligands using PAMPA technique and quantitative-structure permeability relationship analysis
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