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Key Documents

856705P

Avanti

16:0 Lyso PE

Avanti Research - A Croda Brand, powder

Synonyme(s) :

1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; PE(16:0/0:0); 110698, Lysophosphatidylethanolamine 16:0

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About This Item

Formule empirique (notation de Hill):
C21H44NO7P
Numéro CAS:
Poids moléculaire :
453.55
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

Forme

powder

Conditionnement

pkg of 1 × 200 mg (856705P-200mg)
pkg of 1 × 25 mg (856705P-25mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCCCCC)=O

Application

16:0 Lyso PE has been used to degranulate human eosinophils. It has also been used to enhance nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) phosphorylation.

Conditionnement

5 mL Amber Glass Screw Cap Vial (856705P-200mg)
5 mL Amber Glass Screw Cap Vial (856705P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells
Itakura A, et al.
FEBS Open Bio, 3(1), 243-251 (2013)
Miki Eto et al.
International journal of molecular sciences, 13(12), 16267-16280 (2012-12-05)
Cellular membranes contain glycerophospholipids, which have important structural and functional roles in cells. Glycerophospholipids are first formed in the de novo pathway (Kennedy pathway) and are matured in the remodeling pathway (Lands' cycle). Recently, lysophospholipid acyltransferases functioning in Lands' cycle
Yoko Shima et al.
The Journal of biological chemistry, 295(20), 6983-6991 (2020-04-10)
Newly synthesized major histocompatibility complex (MHC) class I proteins are stabilized in the endoplasmic reticulum (ER) by binding 8-10-mer-long self-peptide antigens that are provided by transporter associated with antigen processing (TAP). These MHC class I:peptide complexes then exit the ER
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
Wuhanqimuge et al.
FEBS open bio, 3, 243-251 (2013-06-19)
Lysophosphatidylcholine (LPC) is one of the major lysophospholipids mainly generated by phospholipase A2 (PLA2)-mediated hydrolysis of phosphatidylcholine (PC). We previously found that LPC displays neurotrophin-like activity in the rat pheochromocytoma PC12 cells and in cerebellar granule neurons, but the molecular

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