840035C

18:1 PS (DOPS)

Avanti Research^™ - A Croda Brand

• Synonyme(s) : 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))
• Formule empirique (notation de Hill): C₄₂H₇₇NO₁₀PNa
• Numéro CAS: 90693-88-2
• Poids moléculaire : 810.03
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Description: 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
• Pureté: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 1 mL (840035C-10mg); pkg of 1 × 2.5 mL (840035C-25mg); pkg of 2 × 4 mL (840035C-200mg); pkg of 5 × 4 mL (840035C-500mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand
• Concentration: 10 mg/mL (840035C-10mg); 10 mg/mL (840035C-25mg); 25 mg/mL (840035C-200mg); 25 mg/mL (840035C-500mg)
• Type de lipide: cardiolipins; phospholipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1
• Clé InChI: KPHZNDUWYZIXFY-YORIBCANSA-M

Description

Description générale

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules. 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) carry a carboxylic acid group and a protonated amine group in their head group.

Application

18:1 PS (DOPS) has been used as a component of supported membrane tubes (SMrT) templates. It has also been used in the preparation of lipid-mixing vesicles, content-mixing vesicles and lipid mixture.

Actions biochimiques/physiologiques

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Conditionnement

30 mL Amber Narrow Mouth Bottle with Screw Cap (840035C-500mg)

5 mL Clear Glass Sealed Ampule (840035C-10mg)

5 mL Clear Glass Sealed Ampule (840035C-200mg)

5 mL Clear Glass Sealed Ampule (840035C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable