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739952

Sigma-Aldrich

Resomer® RG 503, Poly(D,L-lactide-co-glycolide)

lactide:glycolide 50:50, ester terminated, Mw 24,000-38,000

Synonyme(s) :

PLGA, RESOMER® RG 503

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About This Item

Formule linéaire :
[C3H4O2]x[C2H2O2]y
Numéro CAS:
26780-50-7
Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Niveau de qualité

100

Forme

amorphous

Ratio alimentaire

lactide:glycolide 50:50

Poids mol.

Mw 24,000-38,000

Intervalle de dégradation

<3 months

Viscosité

0.32-0.44 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

Température de transition

Tg 44-48 °C

Température de stockage

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

Clé InChI

LCSKNASZPVZHEG-UHFFFAOYSA-N

Catégories apparentées

Application

Controlled release

Informations légales

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCH9991
BCCG5990
BCCF1461
BCCB5545
BCBW9420

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Consulter la Bibliothèque de documents

Kaiping Wang et al.
Journal of microencapsulation, 36(4), 356-370 (2019-06-14)
Here, we have successfully synthesised and purified multifunctional PLGA-based nanoparticles by the co-encapsulation of an anticancer drug (tetrandrine) and a magnetic material (Fe3O4). The obtained Tet-Fe3O4-PLGA NPs had a uniform spherical shape with a particle size of approximately 199 nm and
William A Lackington et al.
Journal of controlled release : official journal of the Controlled Release Society, 304, 51-64 (2019-05-06)
Neurotrophic factor delivery via biodegradable nerve guidance conduits may serve as a promising treatment for the repair of large peripheral nerve defects. However, a platform for controlled delivery is required because of their short in vivo half-life and their potential
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
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