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318434

Sigma-Aldrich

3,3′-Dipropylthiacarbocyanine iodide

98%

Synonyme(s) :

3-Propyl-2-[3-[3-propyl-2(3H)benzothiazolylidene]-1-propenyl]benzothiazolium iodide, DiSC3(3)

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About This Item

Formule empirique (notation de Hill):
C23H25IN2S2
Numéro CAS:
53336-12-2
Poids moléculaire :
520.49
Numéro Beilstein :
3842440
Numéro MDL:
MFCD00013340
Code UNSPSC :
12171500
ID de substance PubChem :
329753928
Nomenclature NACRES :
NA.47

Pureté

98%

Forme

crystalline powder

Pf

288 °C (dec.) (lit.)

Solubilité

chloroform/methanol: 10 mg/mL, clear

λmax

559 nm

ε (coefficient d'extinction)

163120 at 599 nm in methanol at 0.00463 g/L
17425 at 298 nm in methanol at 0.00463 g/L
40246 at 220 nm in methanol at 0.00463 g/L

Fluorescence

λex 559 nm; λem 575 nm in methanol

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

[I-].CCCN1C(\Sc2ccccc12)=C\C=C\c3sc4ccccc4[n+]3CCC

InChI

1S/C23H25N2S2.HI/c1-3-16-24-18-10-5-7-12-20(18)26-22(24)14-9-15-23-25(17-4-2)19-11-6-8-13-21(19)27-23;/h5-15H,3-4,16-17H2,1-2H3;1H/q+1;/p-1

Clé InChI

JGTCEHAVVINOPG-UHFFFAOYSA-M

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Description générale

3,3′-Dipropylthiacarbocyanine iodide is a carbocyanine fluorescent dye sensitive to membrane potential. This cyanine dye plays a vital role as an optical probe of membrane potential. An increase in the fluorescence intensity of the dye indicates depolarization of the plasma membrane potential.

Application

3,3′-Dipropylthiacarbocyanine iodide has been used to determine bacterial membrane permeability by the effect of electrochemical scaffold treatment.

Actions biochimiques/physiologiques

The embrane potential sensitive dye, 3,3′dipropylthiacarbocyanine iodide enters only depolarized cells, where it binds reversibly to lipid-rich intracellular components.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
01221PW

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