112968

Methylhydroquinone

99%

• Synonyme(s) : Toluhydroquinone
• Formule linéaire : CH₃C₆H₃-1,4-(OH)₂
• Numéro CAS: 95-71-6
• Poids moléculaire : 124.14
• Numéro Beilstein : 2041489
• Numéro CE : 202-443-7
• Numéro MDL: MFCD00002345
• Code UNSPSC : 12352100
• ID de substance PubChem : 24847123
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 99%
• Forme: solid
• Température d'inflammation spontanée: 851 °F
• Pf: 128-130 °C (lit.)
• Chaîne SMILES: Cc1cc(O)ccc1O
• InChI: 1S/C7H8O2/c1-5-4-6(8)2-3-7(5)9/h2-4,8-9H,1H3
• Clé InChI: CNHDIAIOKMXOLK-UHFFFAOYSA-N

Description

Description générale

Methylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T.

Application

Methylhydroquinone can be used as a reactant to prepare:

• A semiflexible thermotropic polyester via polycondensation reaction with 4,4′-sebacoyldioxydibenzoyl chloride.
• A sesquiterpene (±)-helibisabonol A.
• poly{hexakis[(methyl)(4-hydroxyphenoxy)]cyclotriphosphazene} by reacting with hexachlorocyclotriphosphazene.
• 6-Hydroxy-4,7-dimethyl-2H-1-benzopyran-2-one by treating with ethyl acetoacetate in the presence of H₂SO₄ as a catalyst.

Actions biochimiques/physiologiques

Methylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies.

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H314,H317,H335,H410
• Conseils de prudence: P260 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 341.6 °F - closed cup
• Point d'éclair (°C): 172 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves