68082
2,4′-Dibromoacetophenone
for HPLC derivatization, LiChropur™, ≥99.0% (HPLC)
Synonym(s):
4′-Bromophenacyl bromide
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About This Item
Recommended Products
grade
for HPLC derivatization
Quality Level
Assay
≥99.0% (HPLC)
form
solid
quality
LiChropur™
technique(s)
HPLC: suitable
mp
108-110 °C (lit.)
108-112 °C
SMILES string
BrCC(=O)c1ccc(Br)cc1
InChI
1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
InChI key
FKJSFKCZZIXQIP-UHFFFAOYSA-N
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Application
Derivatisation reagent for HPLC separation of free fatty acids (FFAs) in human plasma, for liquid chromatography-UV-tandem mass spectrometric analysis of perfluorinated carboxylic acids.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Journal of chromatography. B, Biomedical sciences and applications, 719(1-2), 9-23 (1998-12-30)
We report a rapid and sensitive method for separation and quantitation of free fatty acids (FFAs) in human plasma using high-performance liquid chromatography (HPLC). Two established techniques of lipid extraction were investigated and modified to achieve maximal FFA recovery in
Journal of chromatography. A, 1235, 132-140 (2012-03-10)
The presence of perfluorocarboxylates (PFCAs) in the environment is of increasing concern due to their possible toxicity to humans and bioaccumulation in organisms. PFCAs are frequently found in river water, sediment and organisms and sometimes even in groundwater. In order
Toxicology letters, 185(2), 102-109 (2009-01-03)
In view of the controversial role of catalytic activity on the cytotoxicity of phospholipase A(2) (PLA(2)), the present study is conducted to explore whether PLA(2) induces apoptotic process of human leukemia U937 cells through catalytic activity-independent pathway. Modification of His-48
Acta crystallographica. Section D, Biological crystallography, 61(Pt 12), 1670-1677 (2005-11-23)
The crystal structure of an acidic phospholipase A(2) isolated from Bothrops jararacussu venom (BthA-I) chemically modified with p-bromophenacyl bromide (BPB) has been determined at 1.85 Angstroms resolution. The catalytic, platelet-aggregation inhibition, anticoagulant and hypotensive activities of BthA-I are abolished by
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 142(3-4), 371-381 (2006-01-31)
MjTX-II, a myotoxic phospholipase A(2) (PLA(2)) homologue from Bothrops moojeni venom, was functionally and structurally characterized. The MjTX-II characterization included: (i) functional characterization (antitumoral, antimicrobial and antiparasitic effects); (ii) effects of structural modifications by 4-bromophenacyl bromide (BPB), cyanogen bromide (CNBr)
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