SAB4300188

Anti-phospho-EIF4E (pSer²⁰⁹) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CBP antibody produced in rabbit, Anti-EIF4E1 antibody produced in rabbit, Anti-EIF4EL1 antibody produced in rabbit, Anti-EIF4F antibody produced in rabbit, Anti-eukaryotic translation initiation factor 4E antibody produced in rabbit
• MDL number: MFCD03455733
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~25 kDa
• species reactivity: mouse, human, rat
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (S-G-SP-T-T)
• NCBI accession no.: NP_001124150.1
• UniProt accession no.: P06730
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer209)
• Gene Information: human ... EIF4E(1977)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 209 (S-G-S(p)-T-T), according to the protein EIF4E.

Features and Benefits

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Target description

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable