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Sigma-Aldrich

Nitrous oxide

99%

Synonym(s):

Dinitrogen monoxide, Laughing gas

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About This Item

Empirical Formula (Hill Notation):
N2O
CAS Number:
10024-97-2
Molecular Weight:
44.01
Beilstein:
8137358
EC Number:
233-032-0
MDL number:
MFCD00011492
UNSPSC Code:
12142100
PubChem Substance ID:
24857798
NACRES:
NA.22

vapor density

1.53 (15 °C, vs air)

Quality Level

100

vapor pressure

51.7 mmHg ( 21 °C)

Assay

99%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

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Application

  • Nitrous oxide allows selective oxygen atom transfer reactions while minimizing the risk of over-oxidation. Therefore, it is used to oxidize disilenes, silanimines, silaethenes and silylenes.
  • Along with Ru-porphyrin catalyst, it can be used in the epoxidation of olefins and steroids.
  • It can be used as an oxidant in for the metal-catalyzed oxidative homo- and cross-coupling of Grignard reagents.
  • N2O can also be used as a nitrogen-dopant source to synthesize p-type zinc oxide nanowires (ZnO NWs) via vapor-liquid-solid growth.

Packaging

Supplied in a carbon steel lecture bottle with a CGA180M/CGA110F needle valve installed.

Compatible with the following:
  • Aldrich® lecture-bottle station systems
  • Aldrich® lecture-bottle gas regulators

Other Notes

See Technical Information Bulletin AL-151 Gas Regulators: Selection, Installation, and Operation

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC

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Signal Word

Danger

Hazard Statements

H270,H280,H336

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

2A - Gases

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthetic chemistry with nitrous oxide.
Severin K.
Chemical Society Reviews, 44(17), 6375-6386 (2015)
Nitrous oxide oxidation of olefins catalyzed by ruthenium porphyrin complexes.
Yamada T, et al.
Chemistry Letters (Jpn), 30(3), 268-269 (2001)
p-type ZnO nanowire arrays.
Yuan G D, et al.
Nano Letters, 8(8), 2591-2597 (2008)
Oxidative Coupling Reactions of Grignard Reagents with Nitrous Oxide.
Kiefer G, et al.
Angewandte Chemie (International Edition in English), 52(24), 6302-6305 (2013)
Git Lidman et al.
Developmental medicine and child neurology, 57(8), 754-761 (2015-03-27)
To investigate the effects of repeated botulinum toxin A (BoNT-A) injections combined with occupational therapy, including a splint, compared with occupational therapy alone on hand function in children with unilateral spastic cerebral palsy (USCP), in all International Classification of Functioning
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