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1134030

USP

Ciclopirox olamine

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolammonium salt

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About This Item

Formule empirique (notation de Hill):
C12H17NO2 · C2H7NO
Numéro CAS:
41621-49-2
Poids moléculaire :
268.35
Numéro MDL:
MFCD00078997
Code UNSPSC :
41116107
ID de substance PubChem :
329749395
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

ciclopirox

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

NCCO.CC1=CC(=O)N(O)C(=C1)C2CCCCC2

InChI

1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2

Clé InChI

MBRHNTMUYWQHMR-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ciclopirox olamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ciclopirox Olamine Cream
  • Ciclopirox Olamine Topical Suspension

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

C2162700

Ciclopirox olamine, European Pharmacopoeia (EP) Reference Standard

C2162702

Ciclopirox impurity B, European Pharmacopoeia (EP) Reference Standard

C2162701

Ciclopirox impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000040

Ciclopirox, European Pharmacopoeia (EP) Reference Standard

1134040

Ciclopirox Related Compound B, United States Pharmacopeia (USP) Reference Standard

1134018

Ciclopirox, United States Pharmacopeia (USP) Reference Standard

1134084

Ciclopirox Related Compound C, United States Pharmacopeia (USP) Reference Standard

1134029

Ciclopirox Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR1920

Ciclopirox, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2854

Ciclopirox Related Compound B, certified reference material, pharmaceutical secondary standard

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Conseils de prudence

P305 + P351 + P338

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Ken Fujimura et al.
Cancer research, 74(22), 6671-6681 (2014-09-28)
Deregulation of protein synthesis is a hallmark of cancer cell proliferation, survival, and metastatic progression. eIF5A1 and its highly related isoform eIF5A2 are translation initiation factors that have been implicated in a range of human malignancies, but how they control
Vanessa Alves Pinheiro et al.
Pharmaceutical development and technology, 20(2), 197-203 (2013-11-30)
With the aim of reducing system absorption and consequently, the side effects, and simultaneously select a penetration enhancing, three topical formulations with 0.5% ciclopirox olamine (CO) and 15% of propylene glycol (PG), ethoxydiglycol or oleic acid were developed and evaluated
Keita Sugiura et al.
Antimicrobial agents and chemotherapy, 58(7), 3837-3842 (2014-04-23)
Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. Keratin affinity of topical drugs is an important physicochemical property impacting therapeutic efficacy.
Anja Täuber et al.
Molecular pharmaceutics, 11(7), 1991-1996 (2014-02-05)
Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. Hence, high efficacy of the active ingredient without systemic

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