1001502

Acepromazine maleate

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : Acetopromazine maleate salt, 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine maleate salt, Acepromazine maleate salt
• Formule empirique (notation de Hill) : C₁₉H₂₂N₂OS · C₄H₄O₄
• Numéro CAS: 3598-37-6
• Poids moléculaire : 442.53
• NACRES: NA.24
• PubChem Substance ID: 329748881
• UNSPSC Code: 41116107
• MDL number: MFCD00082473

Propriétés

• grade: pharmaceutical primary standard
• agency: USP
• API family: acepromazine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC(=O)\C=C/C(O)=O.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(C)=O
• InChI: 1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19;5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: FQRHOOHLUYHMGG-BTJKTKAUSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acepromazine maleate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Acepromazine Maleate Injection
• Acepromazine Maleate Tablets

Biochem/physiol Actions

Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.

Atypical neuroleptic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H336
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - STOT SE 3
• target_organs: Central nervous system
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable