La phase SUPELCOSIL LC-ABZ présente une technologie de désactivation unique qui fournit d′excellentes performances en phase inverse pour les composés basiques, ainsi que pour les composés acides, neutres polaires, et non polaires. Pour obtenir une belle forme de pic avec la phase LC-ABZ, il n′est généralement pas nécessaire de recourir aux techniques d′élimination des silanols telles que l′utilisation d′amines de compétition, l′utilisation d′une force ionique élevée ou l′ajustement du pH des phases mobiles à une valeur extrême.
Caractéristiques et avantages
• Pour acides, bases, zwitterions. • Rétention polaire augmentée par rapport aux phases inverses standards. • Sélectivité unique • Désactivation des silanols. • Forme du pic, efficacité et rétention sont comparables aux phases C8 des substances non polaires.
Produits recommandés
Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Informations légales
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
Journal of chromatography. A, 870(1-2), 105-114 (2000-03-18)
A high-performance liquid chromatographic method with electrochemical detection has been developed for the determination of six 1,4-dihydropyridines: nifedipine, nimodipine, nisoldipine, nicardipine, felodipine and lacidipine. The chromatographic separation was performed using a Supelcosil LC-ABZ+Plus C18 column. A mobile phase of methanol-water
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..