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RES0114M-A7

SAFC

MES sodium salt

Synonyme(s) :

Acide 2-(N-morpholino)éthanesulfonique sodium salt, Acide 4-morpholinoéthanesulfonique sodium salt

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About This Item

Formule empirique (notation de Hill):
C6H12NNaO4S
Numéro CAS:
Poids moléculaire :
217.22
Numéro Beilstein :
3765682
Numéro CE :
Numéro MDL:
Code UNSPSC :
12161700
Nomenclature NACRES :
NA.21

Source biologique

synthetic

Forme

powder

Technique(s)

cell culture | mammalian: suitable

Impuretés

Endotoxin and microbial, tested

Plage de pH utile

5.5-6.7

pKa  

6.1

Adéquation

suitable for manufacturing use

Activité étrangère

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

Chaîne SMILES 

[Na+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

Clé InChI

IRHWMYKYLWNHTL-UHFFFAOYSA-M

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Description générale

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Conditionnement

Product is available in the following package sizes:
RES0114M-A701X: 100g container
RES0114M-A702X 1kg container
RES0114M-A704X: 10kg container
RES0114M-A705X: 25kg container

Informations légales

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Remplacé(e)(s) par

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Yue Yuan et al.
Biochemistry, 50(34), 7350-7360 (2011-08-03)
This study is aimed at investigating the molecular basis of environmental adaptation of woolly mammoth hemoglobin (Hb) to the harsh thermal conditions of the Pleistocene ice ages. To this end, we have carried out a comparative biochemical-biophysical characterization of the
Tsuyoshi Shirai et al.
Journal of molecular biology, 321(5), 879-889 (2002-09-11)
The crystal structure of congerin II, a galectin family lectin from conger eel, was determined at 1.45A resolution. The previously determined structure of its isoform, congerin I, had revealed a fold evolution via strand swap; however, the structure of congerin
Theresa E Bankston et al.
Journal of chromatography. A, 1217(14), 2123-2131 (2010-03-03)
Hydroxyapatite (HAP) columns, widely used for chromatographic separation of proteins and other biomolecules because of their unique selectivity and ability to resolve complex mixtures, exhibit limited stability at acidic conditions requiring careful control of pH. Even with buffered solutions, however
Takamitsu Miyafusa et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 64(Pt 6), 512-515 (2008-06-10)
Capsular polysaccharides (CPs) are important virulence factors of Staphylococcus aureus. The biosynthesis of type 5 and type 8 CPs (CP5 and CP8), which are produced by most clinical isolates of S. aureus, is catalyzed by 16 CP-assembling proteins. One of
Shu-Chih Hsieh et al.
Journal of biomedical materials research. Part A, 99(4), 576-585 (2011-09-29)
For surface modification and nerve regeneration, chitosan, followed by nerve growth factor (NGF), was immobilized onto the interior surface of poly (lactic acit-co-glycolic) conduits, using EDC/NHS/MES system (EDCs) and genipin (GP). Four new conduits were, therefore, obtained and named by

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