P3662

Pyruvate de sodium

Hybri-Max^™, powder, suitable for hybridoma

• Synonyme(s) : αAcide α-cétopropionique sodium salt, Acide 2-oxopropanoïque sodium salt, Acide pyruvique sodium salt
• Formule linéaire : CH₃COCOONa
• Numéro CAS: 113-24-6
• Poids moléculaire : 110.04
• Beilstein: 3568341
• Numéro CE : 204-024-4
• Numéro MDL: MFCD00002586
• Code UNSPSC : 12352205
• ID de substance PubChem : 24898440
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Qualité: Hybri-Max^™
• Essai: ≥99%
• Forme: powder
• Technique(s): cell culture | hybridoma: suitable
• Impuretés: endotoxin, tested
• Pf: >300 °C (lit.)
• Solubilité: H₂O: 100 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• Chaîne SMILES: [Na+].CC(=O)C([O-])=O
• InChI: 1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
• Clé InChI: DAEPDZWVDSPTHF-UHFFFAOYSA-M

Description

Application

Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.[1][2][3][4]

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Actions biochimiques/physiologiques

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia.[5] In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases.[6] Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.[7]

Informations légales

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H317,H319
• Conseils de prudence: P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Sens. 1B
• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)