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Merck
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O3008

Sigma-Aldrich

Oleic Acid-Albumin from bovine serum

liquid, sterile-filtered, BioReagent, suitable for cell culture

Synonyme(s) :

Oleic acid-BSA complex

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About This Item

Numéro MDL:
MFCD00284022
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.75

Stérilité

sterile-filtered

Gamme de produits

BioReagent

Forme

liquid

Composition

Oleic acid, 2 mol/mol albumin

Concentration

100 mg/mL BSA in DPBS
90-120 mg/mL protein (biuret)

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, tested

Température de stockage

2-8°C

Application

Oleic Acid-Albumin from bovine serum has been used: as a component of the Dulbecco′s modified Eagle′s medium (DMEM) to study adipogenic differentiation in chicken embryonic fibroblast cell lines, to study its effects on benign prostate epithelial cells as a component of the cell culture medium to quantify triglycerides in human epithelial colorectal adenocarcinoma cells

Actions biochimiques/physiologiques

Fatty Acid-Albumin - complexes are used as alternative sources of lipids in the development of serum-free media. Fatty acids bind to serum proteins in high proportions. Serum proteins may help in the release of beneficial fatty acids and bind those that are inhibitory. Oleic acid bound to bovine serum albumin (BSA) shows a positive effect on the growth of various cells.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

08168

Timestrip Plus™ 8 °C

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

Certificats d'analyse (COA)

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Yinfang Wang et al.
Journal of experimental & clinical cancer research : CR, 38(1), 147-147 (2019-04-07)
Ionizing radiation (IR) therapy is the standard first-line treatment for newly diagnosed patients with glioblastoma (GBM), the most common and malignant primary brain tumor. However, the effects of IR are limited due to the aberrant radioresistance of GBM. Transcriptome analysis
Sarah Guttmann et al.
PloS one, 15(3), e0230025-e0230025 (2020-03-11)
Intestinal cells control delivery of lipids to the body by adsorption, storage and secretion. Copper (Cu) is an important trace element and has been shown to modulate lipid metabolism. Mutation of the liver Cu exporter ATP7B is the cause of
Maddalena Parafati et al.
International journal of molecular sciences, 21(24) (2020-12-19)
Non-alcoholic fatty liver disease (NAFLD) has a large impact on global health. At the onset of disease, NAFLD is characterized by hepatic steatosis defined by the accumulation of triglycerides stored as lipid droplets. Developing therapeutics against NAFLD and progression to
Alejandro Morales et al.
Laboratory investigation; a journal of technical methods and pathology, 101(7), 921-934 (2021-04-08)
Lipid droplet (LD) accumulation in cancer results from aberrant metabolic reprograming due to increased lipid uptake, diminished lipolysis and/or de novo lipid synthesis. Initially implicated in storage and lipid trafficking in adipocytes, LDs are more recently recognized to fuel key
David M Favara et al.
Metabolites, 9(12) (2019-11-30)
Adhesion G Protein-Coupled Receptor L4 (ADGRL4/ELTD1) is an endothelial cell adhesion G protein-coupled receptor (aGPCR) which regulates physiological and tumour angiogenesis, providing an attractive target for anti-cancer therapeutics. To date, ADGRL4/ELTD1's full role and mechanism of function within endothelial biology
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Articles

Stearic Acid in Cell Culture

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.

Oleic Acid in Cell Culture

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

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