MAK110
MTP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Synonyme(s) :
MTTP Activity Assay Kit, Microsomal triglyceride transfer protein activity assay kit
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About This Item
Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84
Produits recommandés
Utilisation
sufficient for 100 fluorometric tests
Application(s)
pharmaceutical
Méthode de détection
fluorometric
Maladie(s) pertinente(s)
cardiovascular diseases
Température de stockage
2-8°C
Informations sur le gène
human ... MTTP(4547)
Catégories apparentées
Description générale
Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL).[1] MTP is also necessary for assembly and secretion of chylomicrons by the intestine.[1] This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.[1][2]
Application
MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).[3]
Caractéristiques et avantages
Compatible with high-throughput handling systems.
Adéquation
Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.
Principe
The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λEx=465 nm/λEm=535 nm).
Remarque sur l'analyse
En option
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Produit(s) apparenté(s)
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Code de la classe de stockage
10 - Combustible liquids
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