This product is supplied in powder form and needs to be reconstituted. It is soluble in 1.4 M ammonium hydroxide at 25 mg/mL. Please review the product data page at: https://www.sigmaaldrich.com/product/sigma/h9039
H9039
Hémine
from bovine, ≥90%
Synonyme(s) :
Chloro(protoporphyrinato)fer(III), Chlorohémine, Chloroprotoporphyrine IX-fer(III), Chlorure de ferriprotoporphyrine IX, Hémine (chlorure)
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1 G
62,20 €
10 G
409,00 €
100 G
868,00 €
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Changer de vue
1 G
62,20 €
10 G
409,00 €
100 G
868,00 €
About This Item
Formule empirique (notation de Hill) :
C34H32ClFeN4O4
Numéro CAS:
Poids moléculaire :
651.94
Beilstein:
5229914
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
ID de substance PubChem :
Nomenclature NACRES :
NA.61
Produits recommandés
Source biologique
bovine
Essai
≥90%
Forme
powder
Technique(s)
toxicology assay: suitable
Solubilité
1.4 M NH4OH: soluble 25 mg/mL
Température de stockage
2-8°C
Chaîne SMILES
Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C
InChI
1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;
Clé InChI
BTIJJDXEELBZFS-HXFTUNQESA-K
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Description générale
L′hème est une petite molécule qui se trouve dans la circulation sanguine des mammifères, soit libre, soit liée à l′hémoglobine. Elle sert de source secondaire de fer et contient un anneau porphyrine avec un ion Fe2+ appelé hémine. [1]
Application
L′hémine a été utilisée pour étudier la conjugaison, la caractérisation et la toxicité d′un conjugué lipophosphoglycane-acide polyacrylique pour la vaccination contre la leishmaniose.[2]
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Recently got 1G of the product - H9039. Do I have to dissolve in a solution?
1 réponse-
Utile ?
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What is the solvent medium, to dissolve hemin stock powder and what is stock concentration of hemin (H9039)
1 réponse-
This product is tested for solubility at 25 mg/mL in 1.4 M NH4OH. According to a published article, this material is also soluble at 50 mg/mL in 1.0 M NaOH. Please see the link below to review this publication:
https://journals.asm.org/doi/10.1128/iai.01924-05Utile ?
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What is the recommended method of sterilization in a culture medium with Hemin addition? Autoclaving at 112°C or filter sterilization?
1 réponse-
Stock solutions of Hemin are typically added to medium and autoclaved at 121 °C for 15-20 minutes. Stock solutions may also be filter sterilized and added aseptically to sterile medium.
Utile ?
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I couln´t understand when you say: "There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended." Then for Hemin - from bovine we will not have a Exp.date?
1 réponse-
A number of products are not included in expiration testing programs, as there is no indication to conclude they are unstable. The only date shown on the certificate of analysis will be the Release Date. For these products there is no stated Retest, Expiration or Use-by-Date Date. We recommend handling per defined conditions as printed in our product literature and website product descriptions. Products should be routinely inspected by the customer to ensure they perform as expected. For those products, only our standard warranty of 1 year from the date of shipment of products is applicable. For further information on our warranty please refer to terms and conditions of sale.
Utile ?
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What are some applications for Hemin, Product H9039?
1 réponse-
Hemin-agarose has reportedly been prepared for use in affinity chromatography of heme-binding proteins. See Tsutsui, K., Affinity chromatography of heme-binding proteins: Synthesis of hemin-agarose. Meth. Enzymol. 123, 331, (1986). Sigma supplies a hemin agarose, product H6390. Hemin can also be used as a component in culture media for the cultivation of bacteria, such as Leishmania tarentolae.
Utile ?
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What is the shelf life for Hemin, Product H9039?
1 réponse-
There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended.
Utile ?
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What is the Department of Transportation shipping information for this product?
1 réponse-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Utile ?
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How stable is Hemin, Product H9039, in solution?
1 réponse-
Sigma-Aldrich has not evaluated the solution stability of hemin solutions. Also, we have not found any information on solution storage in the literature. We recommend that solutions be prepared fresh.
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