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C6241

Sigma-Aldrich

Charcoal, Dextran Coated

Synonyme(s) :

Dextran coated charcoal

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79,00 €
20 G
242,00 €

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5 G
79,00 €
20 G
242,00 €

About This Item

Numéro CE :
231-153-3
Code UNSPSC :
12141908
Nomenclature NACRES :
NC.07

79,00 €

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Devis pour commande en gros

Forme

powder

Description générale

Charcoal, Dextran Coated is made from acid washed charcoal powder and dextran, molecular weight 64-76kDa, combined in a 10:1 (w/w) ratio.

Application

Charcoal, Dextran Coated has been used:
  • as a supplement in cell culture media to test the functioning of androgen receptor[1]
  • in the procedure of melatonin radioimmunoassay[2]
  • for the preparation of steroid-free human serum[3]
  • to reduce the creatinine level in untreated serum.

Actions biochimiques/physiologiques

The use of dextran-coated charcoal makes the immunoassay of insulin in biological fluids simpler and more rapid. In theory, the charcoal coated with dextran will adsorb the free hormone and leave hormones that are bound to a carrier (or antibody). Dextran coated charcoal is used to strip hormones from serum instead of charcoal alone, because there is less loss of protein using dextran coated charcoal.[4][5]

Autres remarques

Dry preparation of dextran-treated charcoal

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000221960
0000221954
0000256519
SLCG1377
SLBV2046

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Dextrane from Leuconostoc spp.

Activated charcoal acid-washed with hydrochloric acid

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Supelco

1.02186

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Activated Charcoal meets USP testing specifications

Sigma-Aldrich

C7606

Activated Charcoal

Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison's disease.
Methlie P
Endocrine Connections (2013)
Shih-Hsing Leir et al.
Cell and tissue research, 381(2), 327-336 (2020-05-08)
Organoid cultures derived from primary human tissues facilitate the study of disease processes and the development of new therapeutics. Most men with cystic fibrosis (CF) are infertile due to defects in the epididymis and vas deferens; however, the causative mechanisms
Liang Shi et al.
Cell death & disease, 8(11), e3171-e3171 (2017-11-17)
Hepatocellular carcinoma (HCC) is a heterogeneous malignancy as a result of complex genetic and epigenetic alterations. HCC is characterized by a clear gender disparity for which there is lack of a clear mechanistic understanding. Androgen receptor (AR) is thought to
Modern Methods of Steroid Analysis (2012)
Coated charcoal immunoassay of insulin.
Herbert V
The Journal of Clinical Endocrinology and Metabolism, 25, 1375-1384 (1965)
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Questions

1–2 sur 2 questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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