The product impurities are not identified or quantified. Please see the product specification sheet:
https://www.sigmaaldrich.com/specification-sheets/457/256/A9043-BULK________SIGMA____.pdf.
A9043
S-Acetylthioglycolic acid N-hydroxysuccinimide ester
≥95% (TLC), powder
Synonyme(s) :
N-Succinimidyl (acetylthio)acetate, N-Succinimidyl S-acetylthioglycolate, S-Acetylthioglycolic acid NHS ester, SATA
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10 MG
43,50 €
50 MG
84,90 €
100 MG
142,00 €
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Changer de vue
10 MG
43,50 €
50 MG
84,90 €
100 MG
142,00 €
About This Item
Formule empirique (notation de Hill):
C8H9NO5S
Numéro CAS:
Poids moléculaire :
231.23
Beilstein:
7815491
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Produits recommandés
Niveau de qualité
Essai
≥95% (TLC)
Forme
powder
Solubilité
acetonitrile: 50 mg/mL
DMF: soluble
Température de stockage
−20°C
Chaîne SMILES
CC(=O)SCC(=O)ON1C(=O)CCC1=O
InChI
1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
Clé InChI
FLCQLSRLQIPNLM-UHFFFAOYSA-N
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Application
Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Autres remarques
Note that the ester couples very efficiently to primary amines compared to other thiolating reagents. In addition, this reagent will neutralize original amine positive charge.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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The mercaptoacetyltriglycine (MAG3) chelator has been shown to stably complex technetium-99m (99mTc) for nuclear imaging and radiorhenium (186/188Re) for tumor radiation therapy studies. The bifunctional N-hydroxysuccinimidyl ester of MAG3 with S-acetyl protection (N-hydroxysuccinimidyl S-acetylmercaptoacetyltriglycinate (NHS-MAG3)) has been successfully used to
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Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,
1 réponse-
Utile ?
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