A1852

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of 30 mg

• Synonyme(s) : ATP disodium hydrate
• Formule linéaire : C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• Numéro CAS: 34369-07-8
• Poids moléculaire : 551.14 (anhydrous basis)
• Numéro CE : 213-579-1
• Numéro MDL: MFCD00150755
• Code UNSPSC : 41106305
• eCl@ss : 32160414
• ID de substance PubChem : 24890593
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: microbial (Corynebacterium sp.)
• Pureté: ≥99% (HPLC)
• Forme: powder
• Conditionnement: vial of 30 mg
• Solubilité: water: 50 mg/mL, clear, colorless
• Température de stockage: −20°C
• Chaîne SMILES: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Clé InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Description

Description générale

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger CAMP. ATP provides the metabolic energy to drive metabolic pumps.

Application

ATP serves as a coenzyme in a wide array of enzymatic reactions.Adenosine 5′-triphosphate (ATP) disodium salt hydrate is used for tissue preparation and maintenance.

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been used:

• in rat hippocampal slice cultures to mimic synaptic signalling
• in the isolation of plasmid from primary porcine alveolar macrophages (PAMs)
• as a component of hot reaction kinase buffer for in gel kinase assay

Actions biochimiques/physiologiques

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)