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Y0000635

Modafinil

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-[(Diphenylmethyl)sulfinyl]­acetamide

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About This Item

Formule empirique (notation de Hill):
C15H15NO2S
Numéro CAS:
68693-11-8
Poids moléculaire :
273.35
Numéro MDL:
MFCD00868082
Code UNSPSC :
41116107
ID de substance PubChem :
329831065
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

modafinil

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

NC(=O)CS(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)

Clé InChI

YFGHCGITMMYXAQ-UHFFFAOYSA-N

Informations sur le gène

human ... SLC6A3(6531)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Modafinil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H361d

Classification des risques

Acute Tox. 4 Oral - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Perrin Kwek et al.
European journal of pharmacology, 699(1-3), 132-140 (2012-12-12)
Modafinil is a wakefulness-promoting agent with possible beneficial effects for the management of addiction and in psychiatric conditions, but also with abuse potential of its own. The mechanism of action of modafinil remains unclear. We studied pharmacological mechanisms in the
Tristan Shuman et al.
Behavioural brain research, 235(2), 105-112 (2012-09-12)
Modafinil is a wake-promoting drug effective at enhancing alertness and attention with a variety of approved and off-label applications. The mechanism of modafinil is not well understood but initial studies indicated a limited abuse potential. A number of recent publications
Modafinil and armodafinil in schizophrenia.
Chittaranjan Andrade
The Journal of clinical psychiatry, 73(8), e1062-e1064 (2012-09-13)
Brigitte Lesur et al.
Chemical biology & drug design, 81(3), 429-432 (2012-11-01)
In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually.
K M Baradhi et al.
Transplantation proceedings, 45(2), 845-847 (2013-03-19)
Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys. While the most common etiology being drug-induced, other causes are infectious, autoimmune, and idiopathic forms of disease. Drug-induced acute interstitial nephritis is not only uncommon in
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