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Y0000471

Buspirone for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Buspirone hydrochloride, N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride

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About This Item

Formule empirique (notation de Hill):
C21H31N5O2 · HCl
Numéro CAS:
33386-08-2
Poids moléculaire :
421.96
Numéro MDL:
MFCD00078569
Code UNSPSC :
41116107
ID de substance PubChem :
329830975
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

buspirone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Cl[H].O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4

InChI

1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H

Clé InChI

RICLFGYGYQXUFH-UHFFFAOYSA-N

Informations sur le gène

human ... HTR1A(3350)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Buspirone for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

5-HT1A serotonin receptor agonist; anxiolytic.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000131

Buspirone hydrochloride, European Pharmacopoeia (EP) Reference Standard

1078802

Buspirone hydrochloride, United States Pharmacopeia (USP) Reference Standard

1078573

Buspirone Related Compound A, United States Pharmacopeia (USP) Reference Standard

1078824

Buspirone Related Compound L, United States Pharmacopeia (USP) Reference Standard

1078835

Buspirone Related Compound N, United States Pharmacopeia (USP) Reference Standard

1078813

Buspirone Related Compound G, United States Pharmacopeia (USP) Reference Standard

1078642

Buspirone Related Compound K, United States Pharmacopeia (USP) Reference Standard

PHR1917

Buspirone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2845

Buspirone Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2846

Buspirone Related Compound G, certified reference material, pharmaceutical secondary standard

PHR2847

Buspirone Related Compound K, pharmaceutical secondary standard, certified reference material

PHR2848

Buspirone Related Compound N

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jack Bergman et al.
The international journal of neuropsychopharmacology, 16(2), 445-458 (2012-07-26)
Converging lines of evidence indicate that elevations in synaptic dopamine levels play a pivotal role in the reinforcing effects of cocaine, which are associated with its abuse liability. This evidence has led to the exploration of dopamine receptor blockers as
Feng Qiu et al.
Biomedical chromatography : BMC, 27(2), 233-239 (2012-06-19)
This study firstly describes the development of an accurate and sensitive high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for the quantification of Taiwanin E methyl ether (TEME) in rat plasma. The assay involved a simple liquid-liquid extraction step with ethyl
Long Yuan et al.
Bioanalysis, 4(23), 2795-2804 (2012-12-12)
A dried blood spot (DBS) bioanalysis assay involves many steps, such as the preparation of standard (STD) and QC samples in blood, the spotting onto DBS cards, and the cutting-out of the spots. These steps are labor intensive and time
C Loane et al.
Brain research, 1461, 111-118 (2012-05-23)
Buspirone is an anxiolytic drug and is a partial agonist for the serotonin 5-HT(1A) receptors as well as possessing low affinity and is an antagonist for the dopamine D(2) autoreceptors, with some evidence of a weak affinity to 5-HT(2) receptors.
Repurposing buspirone for drug addiction treatment.
Bernard Le Foll et al.
The international journal of neuropsychopharmacology, 16(2), 251-253 (2012-11-24)
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