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R8881

Sigma-Aldrich

Rhodamine B isothiocyanate–Dextran

Powder

Synonyme(s) :

RITC-Dextran

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About This Item

Numéro MDL:
MFCD00132176
Code UNSPSC :
12171500
Nomenclature NACRES :
NA.47

product name

Rhodamine B isothiocyanate–Dextran, average mol wt ~10,000

Forme

powder

Niveau de qualité

200

Poids mol.

average mol wt ~10,000

Ampleur du marquage

0.002-0.01 mol RITC per mol glucose

Couleur

light pink to red
very dark purple

Solubilité

water: 10 mg/mL, clear, pink

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

2-8°C

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Catégories apparentées

Description générale

Rhodamine B is a thiol-reactive and photostable fluorescent dye. Rhodamine B isothiocyanate is an aminoxanthene that possesses carboxylic acid and isothiocyanate substituents on the pendant phenyl ring.

Application

Rhodamine B isothiocyanate (NE)-labeled dextran is often used as a fluorescent probe for studies of endocytotic activity and to detect the migrated of marked cells. It is also suitable for perfusion studies in animals. Rhodamine B isothiocyanate–Dextran has been used for in vivo zebrafish blood-brain barrier (BBB) dye diffusion assay.
Dextran labeled with rhodamine B isothiocyanate for possible use in perfusion studies in animals.

Actions biochimiques/physiologiques

Rhodamine B stains the tissue in red-violet color and emits a bright red color when fluoresced. It is highly preferred for marking insects.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000360262
0000374059
0000374059
0000360262
0000309711

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Xiaotong Wu et al.
Journal of molecular cell biology, 10(6), 479-493 (2018-07-31)
Oocytes, the irreplaceable gametes for generating a new organism, are matured in the ovary of living female animals. It is unknown whether any genetic manipulations can be applied to immature oocytes inside the living ovaries. As a proof-of-concept, we here
Specific binding of a mutated fragment of Clostridium perfringens enterotoxin to endothelial claudin-5 and its modulation of cerebral vascular permeability
Zhuangbin Liao
Neuroscience (2016)
Jeremy Gingrich et al.
Chemosphere, 263, 128304-128304 (2020-11-07)
Gap junction intercellular communication (GJIC) is necessary for ovarian function, and it is temporospatially regulated during follicular development and ovulation. At outermost layer of the antral follicle, theca cells provide structural, steroidogenic, and vascular support. Inter- and extra-thecal GJIC is
Ruitao Su et al.
Science advances, 6(41) (2020-10-11)
Microfluidic devices fabricated via soft lithography have demonstrated compelling applications such as lab-on-a-chip diagnostics, DNA microarrays, and cell-based assays. These technologies could be further developed by directly integrating microfluidics with electronic sensors and curvilinear substrates as well as improved automation
Jiawei Sun et al.
Development (Cambridge, England), 145(19) (2018-08-24)
Maternal mRNAs and proteins dictate early embryonic development before zygotic genome activation. In the absence of transcription, elaborate control of maternal mRNA translation is of particular importance for oocyte maturation and early embryogenesis. By analyzing zebrafish ybx1 mutants with a
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