PHR1908

Acetazolamide

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : Acetazolamide, 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide, N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide
• Formule empirique (notation de Hill) : C₄H₆N₄O₃S₂
• Numéro CAS: 59-66-5
• Poids moléculaire : 222.25
• UNSPSC Code: 41116107
• NACRES: NA.24
• EC Number: 200-440-5
• MDL number: MFCD00003105

Propriétés

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to Ph. Eur. A0100000, traceable to USP 1005004
• API family: acetazolamide
• CofA: current certificate can be downloaded
• packaging: pkg of 5 g
• application(s): pharmaceutical
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC(=O)Nc1nnc(s1)S(N)(=O)=O
• InChI: 1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
• InChI key: BZKPWHYZMXOIDC-UHFFFAOYSA-N
• Gene Information: human ... CA1(759), CA12(771), CA2(760), CA4(762)

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

Carbonic anhydrase inhibitor; increases cerebral blood flow.

Biochem/physiol Actions

Inhibits water permeability of membranes by interacting with aquaporins

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB0911 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H315,H319
• Mentions de précaution: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable