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P5631

Sigma-Aldrich

o-Cresolphthalein Complexone

powder

Synonyme(s) :

o-Cresolphthalein-3′,3′′-bis-methyleneiminodiacetic acid, o-Cresolphthalexon, Metal phthalein, Phthalein purple, Xylenylphthalein-bisiminodiacetic acid

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About This Item

Formule empirique (notation de Hill):
C32H32N2O12
Numéro CAS:
Poids moléculaire :
636.60
Numéro Beilstein :
381994
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.47

Forme

powder

Niveau de qualité

Couleur

white to off-white

Pf

181-185 °C (dec.) (lit.)

Solubilité

methanol: 1 mg/mL

Adéquation

suitable for determination of calcium

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

Cc1cc(cc(CN(CC(O)=O)CC(O)=O)c1O)C2(OC(=O)c3ccccc23)c4cc(C)c(O)c(CN(CC(O)=O)CC(O)=O)c4

InChI

1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)

Clé InChI

IYZPEGVSBUNMBE-UHFFFAOYSA-N

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Description générale

o-Cresolphthalein Complexone is a pH indicator dye commonly used for the calorimetric determination of calcium in serum.

Application

o-Cresolphthalein Complexone has been used in the estimation of calcium in serum samples based on the reaction of Ca2+ with o-cresolphthalein complexone in an alkaline solution.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

C M Corns et al.
Annals of clinical biochemistry, 24 ( Pt 4), 345-351 (1987-07-01)
The reasons for the non-linearity of the standard curve for the calcium-cresolphthalein complexone reaction have been investigated. Calcium forms both 1:1 and 2:1 complexes with cresolphthalein complexone; at low calcium concentrations the 1:1 complex predominates and causes non-linearity. At high
J Toffaletti et al.
Clinical chemistry, 26(11), 1562-1565 (1980-10-01)
We adapted a method for dialyzable calcium from fluorometric detection by use of calcein to a more specific spectrophotometric determination with cresolphthalein complexone. The reagents are available commercially and perform satisfactorily with respect to noise level, drift, stability, and sensitivity.
James H Wible et al.
Radiology, 233(1), 158-164 (2004-09-30)
To measure serum calcium concentration with three different analytic methods after administration of gadoversetamide and three other gadolinium chelates in dogs. Six dogs were injected with 0.1-, 0.3-, 1.0-, and 3.0-mmol/kg doses of gadoversetamide; 1.0-mmol/kg doses of gadodiamide, gadopentetate, and
C M Corns
Annals of clinical biochemistry, 27 ( Pt 2), 152-155 (1990-03-01)
The spectral interference caused by haemoglobin in the calcium-cresolphthalein complexone reaction was investigated. The results show that the nature of the haemoglobin derivative in the reaction mixture influences the degree of interference; in turn, the derivative formed depends on the
R J Liedtke et al.
Clinical chemistry, 27(12), 2025-2028 (1981-12-01)
We describe an automated method for calcium assay, for use with the Cobas-Bio centrifugal analyzer. Calcium is reacted with cresolphthalein complexone and the absorbance of the calcium--dye complex at 575 nm is measured. EDTA is then added to break up

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