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L0600000

Lidocaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Lidocaine hydrochloride monohydrate, 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride monohydrate, Lignocaine hydrochloride monohydrate, Xylocaine hydrochloride monohydrate

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About This Item

Formule empirique (notation de Hill):
C14H22N2O · HCl · H2O
Numéro CAS:
6108-05-0
Poids moléculaire :
288.81
Numéro MDL:
MFCD00150329
Code UNSPSC :
41116107
ID de substance PubChem :
329817368
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

lidocaine

Fabricant/nom de marque

EDQM

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2

Clé InChI

YECIFGHRMFEPJK-UHFFFAOYSA-N

Informations sur le gène

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lidocaine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1034

Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material

1366002

Lidocaine, United States Pharmacopeia (USP) Reference Standard

L0595000

Lidocaine, European Pharmacopoeia (EP) Reference Standard

PHR1669

2,6-Dimethylaniline, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1671

Lidocaine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1673

Lidocaine Related Compound H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1670

Lidocaine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1672

Lidocaine Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1674

Lidocaine Related Compound I, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1675

Lidocaine Related Compound J, Pharmaceutical Secondary Standard; Certified Reference Material

1366080

Lidocaine Related Compound H, United States Pharmacopeia (USP) Reference Standard

1366013

Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP727

Lidocaine, British Pharmacopoeia (BP) Reference Standard

BP214

Lidocaine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1995

Lidocaine Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1994

Lidocaine Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Shiran Katabi et al.
STAR protocols, 5(2), 103081-103081 (2024-05-25)
Extracellular recordings in behaving animals are useful for establishing associations between neuronal activity and behavior. Here, we describe how to record in the external globus pallidus (GPe) of monkeys engaged in a behavioral task. We detail the stereotaxic surgery for
Shaun Mehta et al.
JAMA facial plastic surgery, 16(6), 414-418 (2014-09-12)
This study evaluates the postoperative outcomes achieved with incisionless otoplasty for the correction of prominauris. To determine whether incisionless otoplasty is a reliable and replicable technique in correcting prominauris. This study consisted of a retrospective electronic medical record review for
Fang-Chi Yang et al.
Neurobiology of learning and memory, 112, 186-194 (2013-07-31)
Learning active or reactive responses to fear involves different brain circuitry. This study examined how the nuclus accumbens (NAc), dorsal hippocampus (DH) and medial prefrontal cortex (mPFC) may interact in memory processing for these two kinds of responses. Male Wistar
Mark C Tucci et al.
The European journal of neuroscience, 40(6), 2971-2979 (2014-06-18)
A previous analysis of the quinpirole sensitisation rat model of obsessive-compulsive disorder revealed that the behavioral phenotype of compulsive checking consists of three constitutive components - vigor of checking performance, focus on the task of checking, and satiety following a
S Picardi et al.
British journal of anaesthesia, 112(2), 370-379 (2013-09-26)
Signalling of several G-protein-coupled receptors of the Gq/11 family is time-dependently inhibited by local anaesthetics (LAs). Since LA-induced modulation of muscarinic m1 and m3 receptor function may explain their beneficial effects in clinical practice, such as decreased postoperative cognitive dysfunction
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