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C1800000

Chlorphenamine maleate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(±)-Chlorpheniramine maleate salt

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About This Item

Formule empirique (notation de Hill) :
C16H19ClN2 · C4H4O4
Numéro CAS:
113-92-8
Poids moléculaire :
390.86
Numéro MDL:
MFCD00069225
Code UNSPSC :
41116107
ID de substance PubChem :
329774908
Nomenclature NACRES :
NA.24
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Qualité

pharmaceutical primary standard

Famille d'API

chlorpheniramine

Fabricant/nom de marque

EDQM

Pf

130-135 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

Clé InChI

DBAKFASWICGISY-BTJKTKAUSA-N

Informations sur le gène

human ... HRH1(3269)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorphenamine maleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

H1 Histamine receptor antagonist.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1123000

Chlorpheniramine maleate, United States Pharmacopeia (USP) Reference Standard

Y0000436

Chlorphenamine impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000437

Chlorphenamine impurity C, European Pharmacopoeia (EP) Reference Standard

1123135

Chlorpheniramine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1123146

Chlorpheniramine Related Compound C, United States Pharmacopeia (USP) Reference Standard

38595

α-(4-Chlorophenyl)-α-[2-(dimethylamino)ethyl]-2-pyridineacetonitrile hydrochloride, pharmaceutical impurity standard

PHR1647

Chlorpheniramine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1688

Chlorpheniramine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2004

Chlorpheniramine Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

BP081

Chlorphenamine maleate, British Pharmacopoeia (BP) Reference Standard

PHR2103

Chlorphenamine Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2104

2-(4-Chlorophenyl)-4-dimethylaminobutyronitrile hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2105

Chlorphenamine N-Oxide Maleate, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

E L Theunissen et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 34(2), 250-258 (2004-02-28)
Mequitazine is a so-called 'non-sedative' second-generation antihistamine even though it has never been firmly established that this drug's sedative potential actually differs from that of the 'sedative' first-generation antihistamines. The present study compares the sedative effects of three doses of
P van Ruitenbeek et al.
Journal of psychopharmacology (Oxford, England), 22(6), 663-672 (2008-01-23)
Results from recent animal studies suggest an important role for histamine in memory functioning. Histaminergic drugs might prove beneficial for people suffering from memory impairment. To determine if histamine is involved in memory functioning this study evaluates the effects of
Ronilson Agnaldo Moreno et al.
Biomedical chromatography : BMC, 24(7), 774-781 (2009-11-20)
In the present study a fast, sensitive and robust validated method to quantify chlorpheniramine in human plasma using brompheniramine as internal standard (IS) is described. The analyte and the IS were extracted from plasma by LLE (diethyl ether-dichloromethane, 80:20, v/v)
Shirlei Cristina Moreira et al.
Revista da Sociedade Brasileira de Medicina Tropical, 40(5), 591-593 (2007-11-10)
An occurrence of pruritic papular dermatitis among the whole crew of a Filipino commercial ship in Salvador, State of Bahia, was associated with contact with Hylesia moths. This unusual type of dermatitis is caused by the bristles (flechettes) on the
F Brunet-Possenti et al.
Dermatology (Basel, Switzerland), 223(3), 200-202 (2011-10-12)
Primary cutaneous follicle center lymphoma (PCFCL) is the most common cutaneous B cell lymphoma. It is most often indolent and responds well to rituximab. We present a case of transient rituximab-induced edematous lesions located exclusively on tumor papules in a
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