Microorganisms grow under a remarkable range of extreme conditions. Environmental transcriptomic and proteomic studies have highlighted metabolic pathways active in extremophilic communities. However, metabolites directly linked to their physiology are less well defined because metabolomics methods lag behind other omics
As a response to high osmolality, many microorganisms synthesize various types of compatible solutes. These organic osmolytes aid in offsetting the detrimental effects of low water activity on cell physiology. One of these compatible solutes is ectoine. A sub-group of
This study constitutes the first-proof-of-concept of a methane biorefinery based on the multi-production of high profit margin substances (ectoine, hydroxyectoine, polyhydroxyalkanoates (PHAs) and exopolysaccharides (EPS)) using methane as the sole carbon and energy source. Two bubble column bioreactors were operated
Journal of bioscience and bioengineering, 128(3), 332-336 (2019-04-03)
Hydroxyectoine, an ectoine derivative, is the most common compatible solute in halophilic microorganisms for resisting harsh environments. Compatible solutes can be utilized in fields such as cosmetics, medicine, and biochemistry. Moderately halophilic microorganisms produce much less hydroxyectoine as compared with
Applied microbiology and biotechnology, 100(3), 1365-1376 (2015-11-23)
Poly(3-hydroxybutyrate) (PHB) is a common carbon- and energy-storage compound simultaneously produced and degraded into its monomer 3-hydroxybutyrate (3HB) by numerous bacteria and Archae in a metabolic pathway called the PHB cycle. We investigated 3HB as a chemical chaperone capable of
what is Hydroxyectoine used for? can i use it stabilize multiple antibodies in a dry format with polyols
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Hydroxyectoin is an ectoine used by many halophilic microorganisms to protect themselves against the extreme salt and temperature conditions in their natural environment. Ectoines have been shown to stabilize proteins, nucleic acids, membranes, and cells. They do not interfere with enzymatic and binding reactions and are highly compatible with cell metabolism.
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