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MAB16988

Sigma-Aldrich

Anti-Hepatitis B Virus Antibody, core Antigen, clone C1-5, a.a. 74-89

ascites fluid, clone C1-5, Chemicon®

Synonyme(s) :

HBcAg

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

C1-5, monoclonal

Espèces réactives

human, avian

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG2aκ

Conditions d'expédition

wet ice

Spécificité

Reacts with HBcAg (epitope recognized - around amino acid positions 70-80, major C determinant).

SPECIES REACTIVITIES:

Cross-reacts with woodchuck hepatitis virus core antigen (WHcAg), but not with duck hepatitis B virus core antigen (DHcAg).

Immunogène

Epitope: Core Antigen
Recombinant purified HBcAg from E.coli

Application

Anti-Hepatitis B Virus Antibody, core antigen, clone C1-5, a.a. 74-89 is an antibody against Hepatitis B Virus for use in ELISA, IF, IP, WB, IC, IH.
ELISA, immunoblotting, immunoprecipitation, immunofluorescent and immunoperoxidase staining of infected liver tissues and transfected cultured cells. Optimal working dilutions: for immunoblotting - 1:1000; for immunofluorescence - 1:200. Optimal working dilutions must be determined by the end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Forme physique

Ascitic fluid. Liquid in DMEM, containing 0.1% sodium azide.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 12 months.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Cihan Makbul et al.
Microorganisms, 9(5) (2021-05-06)
Hepatitis B virus is a major human pathogen, which forms enveloped virus particles. During viral maturation, membrane-bound hepatitis B surface proteins package hepatitis B core protein capsids. This process is intercepted by certain peptides with an "LLGRMKG" motif that binds
Assembly Pathway of Hepatitis B Core Virus-like Particles from Genetically Fused Dimers.
Holmes, K; Shepherd, DA; Ashcroft, AE; Whelan, M; Rowlands, DJ; Stonehouse, NJ
The Journal of Biological Chemistry null
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly
Stray, Stephen J, et al
Proceedings of the National Academy of Sciences of the USA, 102, 8138-8143 (2005)
The affinities of monoclonal antibodies against core antigen of hepatitis B virus.
Apsalons, U and Bichko, V
Archives of Virology, 134, 393-402 (1994)
V Bichko et al.
Molecular immunology, 30(3), 221-231 (1993-02-01)
Particulate and denatured core protein as well as e-antigen (HBe) of hepatitis B virus (HBV) differ in part immunologically but this has not been studied in sufficient detail. Therefore, in this study the B-cell immune response to native and denatured

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