8.21111

2-Thiazoline-2-thiol

for synthesis

• Synonyme(s) : 2-Thiazoline-2-thiol, 2-Mercaptothiazoline
• Formule empirique (notation de Hill): C₃H₅NS₂
• Numéro CAS: 96-53-7
• Poids moléculaire : 119.21
• Numéro MDL: MFCD00126013
• Code UNSPSC : 12352113
• Numéro de classement CE : 202-512-1
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Forme: powder
• Puissance: 300 mg/kg LD₅₀, oral (Rat)
• pH: 6-7 (20 °C, 10 g/L in H₂O)
• Pf: 101-106 °C
• Température de stockage: 2-30°C
• InChI: 1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
• Clé InChI: WGJCBBASTRWVJL-UHFFFAOYSA-N

Description

Application

• Inducing apoptosis in melanoma cells: A study described a ruthenium(II) complex with 2-mercaptothiazoline ligand inducing selective cytotoxicity by causing DNA damage and apoptosis specifically in melanoma cells, highlighting its potential as a therapeutic agent in oncology (de Melo et al., 2024).
• Antimicrobial and synergistic activities: Thiazoline derivatives, including compounds related to 2-mercaptothiazoline, were studied for their antimicrobial and synergistic effects with conventional antibiotics against multidrug-resistant Staphylococcus aureus, presenting a potential strategy for enhancing antibiotic efficacy (Khan et al., 2020).
• Antimicrobial investigation of metal complexes: The antimicrobial properties of Cd(II) and Sn(II) complexes with 2-mercaptothiazoline were evaluated, underscoring the compound′s role in enhancing the bioactivity of metal-based therapeutics (Gaber et al., 2021).

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable