567703

Spermine NONOate

Complex of nitric oxide (NO) with spermine.

• Synonyme(s) : Spermine NONOate, N-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22
• Formule empirique (notation de Hill): C₁₀H₂₆N₆O₂
• Numéro CAS: 136587-13-8
• Poids moléculaire : 262.35
• Numéro MDL: MFCD00210215
• Code UNSPSC : 12352200

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (UV)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic)
• Couleur: white
• Solubilité: 0.1 M NaOH: soluble; water: soluble
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• InChI: 1S/C10H26N6O2/c11-5-3-8-13-7-1-2-9-15(10-4-6-12)16(18)14-17/h13,18H,1-12H2/p+3
• Clé InChI: QPIOUFBAROSIAN-UHFFFAOYSA-Q

Description

Description générale

Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t_½) of NO release = 230 min (PBS, pH 7.4, 22°C).

Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t_½)in PBS, pH 7.4 is 230 minutes at 22°C. Relatively stable in alkaline solution (≥pH 10.0).

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
Convenient reagent for preparing aqueous solutions of NO

Product does not compete with ATP.

Reversible: no

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Standard Handling (A)

Autres remarques

Ramamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable