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Peroxynitrite

Name: Peroxynitrite
Brand: MM

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A propos de cet article

UNSPSC Code:

41116012

NACRES:

NA.41

eCl@ss:

32160405

Form:

liquid

Le tarif et la disponibilité ne sont pas disponibles actuellement.

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Propriétés

form

liquid

Quality Segment

100

manufacturer/tradename

Upstate^®

technique(s)

western blot: suitable

shipped in

dry ice

Description

General description

Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide.[1]

Application

Peroxynitrite has been used to induce pericyte contraction in mouse brains.[1] It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.[2]

Biochem/physiol Actions

Peroxynitrite (ONOO−) exhibits bactericidal activity.[3] It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration.[1]

Physical form

0.3M NaOH

Analysis Note

Routinely evaluated by treating non-stimulated A431 cells.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Cet article	516620	SCT035	N0409
Sigma-Aldrich 20-107 Peroxynitrite	Sigma-Aldrich 516620 Peroxynitrite	Sigma-Aldrich SCT035 BioTracker 515 Green ONOO- Dye	Sigma-Aldrich N0409 Anti-Nitrotyrosine antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 200
form liquid	form liquid	form -	form buffered aqueous solution
manufacturer/tradename Upstate^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename -	manufacturer/tradename -
technique(s) western blot: suitable	technique(s) -	technique(s) cell based assay: suitable	technique(s) immunohistochemistry (frozen sections): 1:1000 using methacarn-fixed, frozen sections of human Alzheimer′s Disease brain, indirect ELISA: 1:1,000 using nitrated-BSA, indirect immunofluorescence: 1:1,000 using A549 cells metabolically labeled with 3-nitrotyrosine, microarray: suitable, western blot: 1:1,000 using nitrated-BSA
shipped in dry ice	shipped in wet ice	shipped in ambient	shipped in dry ice

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pictograms

GHS05

signalword

Warning

hcodes

H290,H315,H319

pcodes

P234 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313

Hazard Classifications

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

flash_point_f

Not applicable

flash_point_c