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Sigma-Aldrich

Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, FITC conjugate

Upstate®, from mouse

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Conjugué

FITC conjugate

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

monoclonal

Réactivité de l'espèce (prédite par homologie)

all

Fabricant/nom de marque

Upstate®

Technique(s)

immunocytochemistry: suitable

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

phosphorylation (pSer/pThr)

Description générale

This antibody recognizes a variety of proteins that are phosphorylated during mitosis.

Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)

Application

Detect phospho-Ser/Thr-Pro also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, FITC conjugate (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC.
For applications in which an FITC conjugate is advantageous, such as ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualité

routinely evaluated in immunocytochemistry on A431 mitotic cells fixed with 3.7% paraformaldehyde

Forme physique

TBS, pH 8.0, 0.05% sodium azide and 30% glycerol

Stockage et stabilité

Stable for 1 year at -20°C from date of shipment. Store in the dark. For maximum recovery of product, centrifuge the vial.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

William Clay Gustafson et al.
Cancer cell, 26(3), 414-427 (2014-09-02)
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Timothy R Rudd,Katarzyna A Uniewicz,Alessandro Ori,Scott E Guimond,Mark A Skidmore et al.
Organic & Biomolecular Chemistry null
Ekaterina P Lamber et al.
Cancer research, 70(3), 996-1005 (2010-01-28)
BRCA1, the breast cancer- and ovarian cancer-specific tumor suppressor, can be a transcriptional repressor or a transcriptional activator, depending on the promoter context. To identify the genes activated or repressed by BRCA1, we have analyzed microarray results from cells depleted
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Kuang, J, et al.
Molecular Biology of the Cell, 5, 135-145 (1994)
The mitosis-specific monoclonal antibody MPM-2 recognizes phosphoproteins associated with the nuclear envelope in Chlamydomonas reinhardtii cells.
Harper, J D, et al.
European Journal of Cell Biology, 51, 272-278 (1990)

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