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Merck
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03-0162-00

Millipore

SMC® Human IL-22 High Sensitivity Kit

1 kit sufficient for 96 wells, input: serum, plasma

Synonyme(s) :

IL-22 Single Molecule Counting Kit, IL-22 ultra-sensitive immunoassay, IL22 immunoassay kit, Interleukin-22 immunoassay kit

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

 kit sufficient for 96 wells

Espèces réactives

human

Fabricant/nom de marque

SMC®

assay range

sensitivity: 0.10 pg/mL
(lower limit of quantification)
inter-assay cv: <20%
intra-assay cv: <15%
standard curve range: 0.05-50 pg/mL

Technique(s)

ELISA: suitable
single molecule counting: suitable

Entrée

serum
plasma

Compatibilité

for use with SMCxPRO® and Erenna<TMSYMBOL></TMSYMBOL> (validated)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Description générale

The SMC® human IL-22 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.

Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.

Spécificité

Non-human primate plasma: 4 out of 4 individuals found to be detectable.
Feline plasma: 4 out of 4 individuals found to be detectable.
Canine plasma: 4 out of 4 individuals found to be detectable.
Mouse plasma: 5 out 6 individuals found to be detectable.
Although IL-22 was detectable, the assay has not been validated for these species.

Informations légales

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Mahesh Raundhal et al.
Nature immunology, 22(4), 520-529 (2021-03-24)
Patients with myelodysplastic syndromes (MDSs) display severe anemia but the mechanisms underlying this phenotype are incompletely understood. Right open-reading-frame kinase 2 (RIOK2) encodes a protein kinase located at 5q15, a region frequently lost in patients with MDS del(5q). Here we

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