5.06129

α-(Methylamino)isobutyric Acid

• Synonym(s): α-(Methylamino)isobutyric Acid, Neutral Amino Acid Transporter A inhibitor, MeBIA
• Empirical Formula (Hill Notation): C₅H₁₁NO₂
• CAS Number: 2566-34-9
• Molecular Weight: 117.15
• MDL number: MFCD00004191
• UNSPSC Code: 12352106
• NACRES: NA.77

Properties

• Assay: ≥98% (TLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: water: 100 mM
• storage temp.: −20°C
• InChI: 1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
• InChI key: DLAMVQGYEVKIRE-UHFFFAOYSA-N

Description

General description

A glutamine transport inhibitor selective for Na+-dependent amino acid transport system A. Used in studying the functional roles of neurotransmissions mediated by amino acids.

Biochem/physiol Actions

Primary Target
Glutamine transporter

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Young, H., et al., 2013. Am. J. Physiology-Cell Physiology.298, C1401.

Lee, Y., et al., 2013. J. Psych. & Neurosci.: JPN.38, 183.
Blot, A., et al. 2009. Neurosci.164, 998.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable