911461
Polyester bis-MPA dendron, 2 NHBoc, 1 NHS (core)
generation 1
Synonym(s):
Bis-MPA dendron, NHS-NHBoc dendron
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description
NHBoc, 1 NHS (core)
form
solid or liquid
mol wt
generation 1
no. Surface Groups
2
color
colorless to white
functional group
(NHS(core))
storage temp.
−20°C
Related Categories
General description
- Polymer architecture: Dendron
- End Group Functionality: NHBoc
- Bis-MPA : 2,2-bis(hydroxymethyl)propionic acid
Application
Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The NHBoc-functionalized corona and NHS-functionalized core of this product can be readily used in bioconjugation reactions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Progress in Polymer Science, 48, 85-110 (2015)
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
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