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G0400007

Glycerol mono-oleate

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C21H40O4
CAS Number:
25496-72-4
Molecular Weight:
356.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

glyceryl monooleate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

RZRNAYUHWVFMIP-KTKRTIGZSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glycerol mono-oleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Adam M Squires et al.
Langmuir : the ACS journal of surfaces and colloids, 29(6), 1726-1731 (2013-01-26)
We demonstrate a method by which we can produce an oriented film of an inverse bicontinuous cubic phase (Q(II)(D)) formed by the lipid monoolein (MO). By starting with the lipid as a disordered precursor (the L(3) phase) in the presence
Victoria M Steffes et al.
Biomaterials, 145, 242-255 (2017-09-11)
Lipid-based particles are used worldwide in clinical trials as carriers of hydrophobic paclitaxel (PTXL) for cancer chemotherapy, albeit with little improvement over the standard-of-care. Improving efficacy requires an understanding of intramembrane interactions between PTXL and lipids to enhance PTXL solubilization
Josephine Y T Chong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(25), 9223-9232 (2012-05-29)
High-throughput methodologies have been employed to establish structure-property relationships and assess the effectiveness of nonionic steric stabilizers for inverse bicontinuous cubic lyotropic liquid crystalline nanoparticulate dispersions of monoolein and phytantriol. The ability of the stabilizers to disperse the lipids was
Guoliang Zhen et al.
Molecular pharmaceutics, 9(9), 2450-2457 (2012-07-17)
We present studies of the delivery of short interfering ribonucleic acid (siRNA) into a green fluorescent protein (GFP) expressing cell line, using lipid nanocarriers in cubic lyotropic liquid crystal form. These carriers are based on glycerol monooleate (GMO) and employ
Vikas Jain et al.
Biomaterials, 33(29), 7206-7220 (2012-07-20)
A PEGylated drug delivery system of paclitaxel (PTX), based on glyceryl monooleate (GMO) was prepared by optimizing various parameters to explore its potential in anticancer therapy. The prepared system was characterized through polarized light microscopy, TEM, AFM and SAXS to
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