90340

Triethylamine

puriss. p.a., ≥99.5% (GC)

• Synonym(s): N,N-Diethylethanamine
• Linear Formula: (C₂H₅)₃N
• CAS Number: 121-44-8
• Molecular Weight: 101.19
• Beilstein: 605283
• EC Number: 204-469-4
• MDL number: MFCD00009051
• UNSPSC Code: 12352116
• PubChem Substance ID: 57653387
• NACRES: NA.21

Properties

• vapor density: 3.5 (vs air)
• Quality Level: 200
• vapor pressure: 51.75 mmHg ( 20 °C)
• grade: puriss. p.a.
• Assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 593 °F
• shelf life: 36 mo.
• expl. lim.: 8 %
• impurities: ≤0.1% water
• evapn. residue: ≤0.003%
• refractive index: n20/D 1.401 (lit.); n20/D 1.401
• bp: 88.8 °C (lit.)
• mp: −115 °C (lit.)
• density: 0.727 g/mL at 20 °C; 0.726 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.2 mg/kg; Ba: ≤0.1 mg/kg; Bi: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; K: ≤0.5 mg/kg; Li: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Mo: ≤0.02 mg/kg; Na: ≤0.5 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sr: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• functional group: amine
• SMILES string: CCN(CC)CC
• InChI: 1S/C6H15N/c1-4-7(5-2)6-3/h4-6H2,1-3H3
• InChI key: ZMANZCXQSJIPKH-UHFFFAOYSA-N

Description

General description

Triethylamine is a tertiary amine. It has been reported as a promising precipitating reagent for phosphomolybdic acid. Et₃N/formic acid system has been used for the asymmetric transfer hydrogenation (ATH) of methoxy-substituted derivatives.

Triethylamine is a strong base and precipitating agent widely used in Heck reaction and to prepare esters and amides from acyl chlorides.

Application

Triethylamine may be used in the following studies:

• As a base for the Heck reactions.
• Synthesis of spirocycles via Heck cyclization.
• Preparation of triethylammonium picrate and 0.1M triethylamine hydrochloride.

Safety Information

• Pictograms: GHS02,GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H302,H311 + H331,H314,H335
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 12.2 °F - closed cup
• Flash Point(C): -11 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves