Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

161756

Sigma-Aldrich

Bromomethyl methyl ether

technical grade, 90%

Synonym(s):

1-Bromomethyl methyl ether, Bromomethoxymethane, Methoxymethyl bromide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
BrCH2OCH3
CAS Number:
13057-17-5
Molecular Weight:
124.96
MDL number:
MFCD00000171
UNSPSC Code:
12352100
PubChem Substance ID:
24849953
NACRES:
NA.22

grade

technical grade

Assay

90%

form

liquid

refractive index

n20/D 1.456 (lit.)

bp

87 °C (lit.)

density

1.531 g/mL at 25 °C (lit.)

functional group

bromo
ether

storage temp.

2-8°C

SMILES string

COCBr

InChI

1S/C2H5BrO/c1-4-2-3/h2H2,1H3

InChI key

JAMFGQBENKSWOF-UHFFFAOYSA-N

Application

Bromomethyl methyl ether was used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone.

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

80.6 °F - closed cup

Flash Point(C)

27 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW2544
MKCR9212
MKCR0221
MKCQ1432
MKCP7363

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Enantioselective synthesis of the C (18)-C (35) segment of immunosuppressant FK-506 using efficient new methodology.
Corey EJ and Huang H-C.
Tetrahedron Letters, 30(39), 5235-5238 (1989)
Nuclear analogs of β-lactam antibiotics. XVI. Aldol condensations of N-protected 4-tritylthio-2-azetidinones.
Martel A, et al.
Canadian Journal of Chemistry, 61(3), 613-618 (1983)
Archana Prasad et al.
Scientific reports, 6, 39490-39490 (2016-12-22)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with aggregation of TAR DNA-binding protein-43 (TDP-43) in neuronal cells and manifests as motor neuron dysfunction &muscle atrophy. The carboxyl-terminal prion-like domain of TDP-43 can aggregate in vitro into toxic

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service